AYURVEDIC APPROACH FOR THE MANAGEMENT OF KAMALA W.S.R. TO HEPATOCELLULAR JAUNDICE - A CASE STUDY

Most of the people have become used to spicy fast food day by day. This has taken human being far away from the nature. Nowadays alcohol consumption is also increasing day by day. Ayurvedic texts has mentioned hepatocellular jaundice as Kamala. Ancient Acharyas has also mentioned “kamali tu virechanama” as Chikitsa Sutra for Kamala. Patient was treated with an integrated approach of Ayurvedic treatment including Virechana Karma (purgation) and Shaman Chikitsa. Due to frequently intake of Pittakara Aahara (spicy and hot food), it leads to vitiation of Pitta Dosha and Virechana (purgation) is the first line of treatment for Pittadushti. Due to Ushna, Laghu, Rruksha Guna, and having Tikta -Katu Rasa of Patola, Amrita, Kutaki (ingredients of internal medication) enhances digestive capacity by hepato-protective action and Pittasaraka guna. Ayurvedic line of management i.e. Virechana therapy and Shamana Chikitsa are successful in Kamala by removing toxic waste from the body, and by correction of Agni (digestive fire). In our ancient classics, single drug along with compound drug have been mentioned in Kamala. These drugs have Kamalahara properties. These Ayurvedic formulations relieve the symptom of Daurbalya (weakness), Kshudha mandya (Appetite loss), Pitamutrata (yellow discolouration of urine), Hrullasa (nausea) and Udarshoola. Also these drugs reduce bile in blood circulation and normalize the other blood parameter. Here a case report of a 50 Years male was having Kamala (hepatocellular jaundice) who was treated with some Ayurvedic herbs and Virechana like Panchakarma and get effectively result with Ayurvedic management

Incorporating Agile with MDA Case Study: Online Polling System

Nowadays agile software development is used in greater extend but for small organizations only, whereas MDA is suitable for large organizations but yet not standardized. In this paper the pros and cons of Model Driven Architecture (MDA) and Extreme programming have been discussed. As both of them have some limitations and cannot be used in both large scale and small scale organizations a new architecture has been proposed. In this model it is tried to opt the advantages and important values to overcome the limitations of both the software development procedures. In support to the proposed architecture the implementation of it on Online Polling System has been discussed and all the phases of software development have been explained.Comment: 14 pages,1 Figure,1 Tabl

SHUKA DHANYA VARGA (GROUP OF CEREALS): A PREVENTIVE AND CURATIVE PERSPECTIVE

Nutritious diet (Ahara) or we can say balanced diet is the key to follow the first principle of Ayurveda or in order to maintain a healthy life. In Ayurveda Acharya Charak has mentioned regular intake of food articles belongs to different categories of food. Acharya Charak has classified Ahara (diet) in twelve categories. Among these, Shukadhanya is the first one. In modern literature, Shukadhanya has been classified in monocotyledons and energy giving food. Energy giving food mainly includes cereal groups like wheat, rice, maize (corn), oats, Jowar, Ragi, and Bajra. Ancient Acharyas has mentioned some Shukadhanya dravyas with their gunas (qualities) like Shashthika, Vrihi (variety of rice), Yava, wheat, which play an important role in prevention of diseases. These Dravyas are Sheeta (cold in potency), Swadu (sweet in taste), Swadu Vipaka (Sweet in digestion). They are said to be Vatavardhak, Alpavarchasa, Brinhana, Shukrala and Mutral. In modern literature, Shukadhanya Varga has been classified in cereal group. Cereals are enriched with niacin, iron, riboflavin, and thiamine, and most cereals have abundant fibre content, especially barley, oat, and wheat. Cereals also have soluble bran that aids in lowering blood cholesterol level and helps in preventing heart diseases. This article is an attempt to analyze the Shukadhanya Varga mentioned in Ayurveda on a scientific basis

LIFESTYLE MODIFICATION OF OFFICIAL WORKERS W.S.R. TO CORPORATE WORKERS

The people working in big private companies may be considered as corporate workers. Due to changed lifestyle of the official workers, they commonly face psychological stress. This stress is mainly caused by the internal pressure to achieve success in goals. Stress may be considered as a major reason in lowering the body’s own resistance power and as a result may develop physical and mental ailments. Majority of official workers are prone to lifestyle disorders due to poor eating habits, load of work, physical inactivity and wrong body postures. Ayurveda can do very much in this field. In Ayurveda, where stress is known as Sahasa, Acharya Charak has advised to avoid Sahasa as it adversely affects the body. In Ayurveda ancient Acharyas has mentioned some Ayurvedic preparations and daily lifestyle regimen which can be helpful in lifestyle modification of corporate workers. Among these, Abhyanga, yoga exercises and Pranayam play a very important role. Therapeutically, Nasya Karma, and Shirodhara are helpful in reducing the symptoms of lifestyle disorders. Some Ayurvedic preparations has been described by the ancient Acharyas like Shankhapushpi, Bramhi, Jatamansi, Sarasawatarishta, Ashwagandha. This article is an attempt to analyze the lifestyle modifications for corporate workers with the help of Ayurveda, meditation, yoga, physical exercises and balanced diet together play an important role in rejuvenating the health of an individual on physical, mental and emotional level with a combination of benefits like Panchkarma therapy, herbal medicines, good Dinacharya and nutritious diet

Approaches to Impose e-penalty Using Vahan Smart Card for Improving Road and Transport Safety with the Help of ICT: An E-Governanace Endeavour

AbstractWith the help of information communication technology (ICT) and computer science, an effective e-Governance should provide an efficient solution for the offenders, who violate the traffic rules and cause unnatural deaths due to breaking of signals or rash driving in INDIA. Many Government Plans have been executed and running successfully like VAHAN and SARATHI related to transportation. This paper proposed some approaches to penalize the offenders electronically and automatically, who violate the traffic rules on road. Penalty can be imposed on offenders using EPS and Vahan Smart Card with the help of RFID and a software flow with wired and wireless e-centre architecture and hybrid approaches

Sinomenine inhibits microglial activation by Aβ and confers neuroprotection

Abstract Background Neuroinflammation is an important contributor to the development of neurodegenerative diseases, including Alzheimer's disease. Thus, there is a keen interest in identifying compounds, especially from herbal sources, that can inhibit neuroinflammation. Amyloid-β (Aβ) is a major component of the amyloid plaques present in the brains of Alzheimer's disease patients. Here, we examined whether sinomenine, present in a Chinese medicinal plant, prevents oligomeric Aβ-induced microglial activation and confers protection against neurotoxicity. Methods Oligomeric amyloid-β was prepared from Aβ(1-42). Intracellular reactive oxygen species production was determined using the dye 2',7'-dichlorodihydrofluorescin diacetate. Nitric oxide level was assessed using the Griess reagent. Flow cytometry was used to examine the levels of inflammatory molecules. BV2-conditioned medium was used to treat hippocampal cell line (HT22) and primary hippocampal cells in indirect toxicity experiments. Toxicity was assessed using MTT reduction and TUNEL assays. Results We found that sinomenine prevents the oligomeric Aβ-induced increase in levels of reactive oxygen species and nitric oxide in BV2 microglial cells. In addition, sinomenine reduces levels of Aβ-induced inflammatory molecules. Furthermore, sinomenine protects hippocampal HT22 cells as well as primary hippocampal cells from indirect toxicity mediated by Aβ-treated microglial cells, but has no effect on Aβ-induced direct toxicity to HT22 cells. Finally, we found that conditioned medium from Aβ-treated BV2 cells contains increased levels of nitric oxide and inflammatory molecules, but the levels of these molecules are reduced by sinomenine. Conclusions Sinomenine prevents oligomeric Aβ-induced microglial activation, and confers protection against indirect neurotoxicity to hippocampal cells. These results raise the possibility that sinomenine may have therapeutic potential for the treatment of Alzheimer's diseases as well as other diseases that involve neuroinflammation.</p

Performance of Integrated IoT Network with Hybrid mmWave/FSO/THz Backhaul Link

Establishing end-to-end connectivity of Internet of Things (IoT) network with the core for collecting sensing data from remote and hard-to-reach terrains is a challenging task. In this article, we analyze the performance of an IoT network integrated with wireless backhaul link for data collection. We propose a solution that involves a self-configuring protocol for aggregate node (AN) selection in an IoT network, which sends the data packet to an unmanned aerial vehicle (UAV) over radio frequency (RF) channels. We adopt a novel hybrid transmission technique for wireless backhaul employing opportunistic selections combining (OSC) and maximal ratio combining (MRC) that simultaneously transmits the data packet on mmWave (mW), free space optical (FSO), and terahertz (THz) technologies to take advantage of their complementary characteristics. We employ the decode-and-forward (DF) protocol to integrate the IoT and backhaul links and provide physical layer performance assessment using outage probability and average bit-error-rate (BER) under diverse channel conditions. We also develop simplified expressions to gain a better understanding of the system's performance at high signal-to-noise ratio (SNR). We provide computer simulations to compare different wireless backhaul technologies under various channel and SNR scenarios and demonstrate the performance of the data collection using the integrated link.Comment: This work has been submitted to IEEE for possible publicatio

EXPLORING THE ANTI HYLOURINIDASE ACTIVITY OF GMELINA ARBOREA USING IN VITRO METHOD

Gmelina arborea is an important medicament in many anti arthritic drugs in ayurvedic system. Arthritis is complex disease which not only affects the joints but also affect the quality of life of patients.   Clinical data revealed that increase levels of hyaluronidase contribute significantly to cartilage degradation. We evaluated the cartilage protective action of the plant extract   (hydro alcoholic extract Gmelina arborea) by examining its effects on the activities of pure hyaluronidase. A simple spectrophotometric method was used to assay Hyaluronidase activity and to detect the potential of extracts. Hydro-alcoholic extracts of Gmelina arborea root and bark extract showed strong inhibition of hyaluronidase activity. Keywords: Gmelina arborea, Arthritis, Hyaluronidas

Giant fibrosarcoma of anterior abdominal wall: a rare case report and review literature

Adult type fibrosarcoma is very rare malignant soft tissue tumor. It usually arises in soft tissues of extremities, trunk, head and neck. Fibrosarcoma is essentially a diagnosis of exclusion from other spindle cell mesenchymal malignant neoplasm; by definition negative for epithelial, myogenous and neural markers on immunohistochemistry. To the best of our knowledge, very few cases have been reported in the literature. We here report a case of giant fibrosarcoma arising from anterior abdominal wall in a recurrent dermatofibrosarcoma proturbens and managed with surgical excision and reconstruction with meshplasty.